ABSTRACT
We conducted a cluster-randomized trial to measure the effect of community-level mask distribution and promotion on symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in rural Bangladesh from November 2020 to April 2021 (N = 600 villages, N = 342,183 adults). We cross-randomized mask type (cloth versus surgical) and promotion strategies at the village and household level. Proper mask-wearing increased from 13.3% in the control group to 42.3% in the intervention arm (adjusted percentage point difference = 0.29; 95% confidence interval = [0.26, 0.31]). The intervention reduced symptomatic seroprevalence (adjusted prevalence ratio = 0.91 [0.82, 1.00]), especially among adults ≥60 years old in villages where surgical masks were distributed (adjusted prevalence ratio = 0.65 [0.45, 0.85]). Mask distribution with promotion was a scalable and effective method to reduce symptomatic SARS-CoV-2 infections.
Subject(s)
COVID-19/prevention & control , Communicable Disease Control , Health Promotion , Masks , Age Factors , Bangladesh/epidemiology , COVID-19/epidemiology , Cluster Analysis , Female , Humans , Male , Physical Distancing , Public Health , Rural Population , Seroepidemiologic Studies , Sex FactorsABSTRACT
Importance: A slow or incomplete civil registry makes it impossible to determine excess mortality due to COVID-19 and difficult to inform policy. Objective: To quantify the association of the COVID-19 pandemic with excess mortality and household income in rural Bangladesh in 2020. Design, Setting, and Participants: This repeated survey study is based on an in-person census followed by 2 rounds of telephone calls. Data were collected from a sample of 135 villages within a densely populated 350-km2 rural area of Bangladesh. Household data were obtained first in person and subsequently over the telephone. For the analysis, mortality data were stratified by month, age, sex, and household education. Mortality rates were modeled by bayesian multilevel regression, and the strata were aggregated to the population by poststratification. Data analysis was performed from February to April 2021. Exposures: Date and cause of any changes in household composition, as well as changes in income and food availability. Main Outcomes and Measures: Mortality rates were compared for 2019 and 2020, both without adjustment and after adjustment for nonresponse and differences in demographic variables between surveys. Income and food availability reported for January, May, and November 2020 were also compared. Results: Enumerators collected data from an initial 16â¯054 households in January 2020; 14â¯551 households (91%) responded when contacted again by telephone in May 2020, and 11â¯933 households (74%)responded when reached again over the telephone in November 2020, for a total of 58â¯806 individuals (29â¯726 female participants [50.5%]; mean [SD] age, 26.4 [19.8] years). A total of 276 deaths were reported between February and the end of October 2020 for the subset of the population that could be contacted twice over the telephone, slightly below the 289 deaths reported for the same population over the same period in 2019. After adjustment for survey nonresponse and poststratification, 2020 mortality changed by -8% (95% CI, -21% to 7%) compared with an annualized mortality of 6.1 deaths per 1000 individuals in 2019. However, in May 2020, salaried primary income earners reported a 40% decrease in monthly income (from 17â¯485 to 10â¯835 Bangladeshi Taka), and self-employed earners reported a 60% decrease in monthly income (23â¯083 to 8521 Bangladeshi Taka), with only a small recovery observed by November 2020. Conclusions and Relevance: In this study of households in rural Bangladesh, all-cause mortality was lower in 2020 compared with 2019. Restrictions imposed by the government may have limited the scale of the COVID-19 pandemic in rural areas, although economic data suggest that these restrictions need to be accompanied by expanded welfare programs.
Subject(s)
COVID-19 , Cause of Death , Family Characteristics , Income , Pandemics , Rural Population , Adolescent , Adult , Bangladesh , Bayes Theorem , COVID-19/mortality , Child , Educational Status , Employment , Female , Humans , Male , Middle Aged , SARS-CoV-2 , Socioeconomic Factors , Young AdultABSTRACT
A randomized-trial of community-level mask promotion in rural Bangladesh during COVID-19 shows that the intervention tripled mask usage and is a cost-effective means of promoting public health.